Figure 12.  Approximately 20 fold higher concentrations of Qdm peptide [and presumably of surface Qa1-Qdm complexes] are required to protect cells from lysis by Qa1R+ NK cells than to sensitize them to lysis by Qa1-specific CTL
		Lytic units/thousand effectors
Various concentrations of Qdm peptide were added into cytotoxicity assays containing T2Q cells
and graded doses of either Qa1R+ NK cells or the type 2 Qa1-specific CTL cloned 12i.
Susceptibility to lysis was calculated by regression analysis and the amount of killing relative to
that in the absence of peptide [for NK lysis] or in the presence of saturating amounts of peptide
[for CTL lysis] was plotted.
Conclusions
1.  The inclusion peptide system provides a simple and accurate means of quantifying the ability
of peptides to either protect target cells from NK lysis or sensitize them to CTL lysis
2.  50% protection from lysis by Qa1R+ NK cells occurs with about 20nM Qdm, whereas 50% of
maximal sensitization to lysis by Qa1-specific CTL occurs at 20 fold lower doses [1nM]