| Figure 4. CTLL2 cells proliferate efficiently to low
concentrations of IL2 and IL15 |
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| CTLL2 cells
were cultured in serial dilutions of IL2 or IL15 for 3 days. |
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| Conclusions |
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| 1. CTLL2 cells proliferate strongly at low
[20pM] concentrations of IL2. |
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| 2. They also proliferate extremely well at
low concentrations of IL15 demonstrating that |
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| the IL15
preparations used have high biological potency. |
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| 3. The reasons why CTLL2 cells respond
efficiently to IL15 whereas normal T cells do |
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| not, and why
human IL15 is more active on CTLL2 cells than mouse IL15, are unknown. |
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