Journal Publications

Simon Doherty, Julian G. Knight, A. Stephen K. Hashmi, Catherine H. Smyth, Nicholas A. B. Ward, Katharine J. Robson, Sophie Tweedley, Ross W. Harrington, and William Clegg, Organometallics, 2010, 29, 4139

Electrophilic gold(I) complexes of diphenyl- and dicyclohexylphosphino-based KITPHOS monophosphines catalyze the 5-exo-dig cycloisomerization of a range of propargyl amides to afford the corresponding alkylidene oxazolines; in all cases catalysts formed from diphenylphosphino-substituted KITPHOS monophosphines outperformed their dicyclohexylphosphino counterparts as well as that based on triphenylphosphine, an indication that the biaryl/biaryl-like framework may be responsible for imparting high catalyst efficiency.