Professor Michael North

Professor of Organic Chemistry and joint director of the URC in Catalysis and Intensified Processing

 

Synthesis and Conformational Analysis of Peptides

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1.     M. North and G. Pattenden, 'Synthetic Studies towards Cyclic Peptides.  Concise Synthesis of Thiazoline and Thiazole Containing Amino Acids.' Tetrahedron, 1990, 46, 8267-8290.

 

2.     S. Cumberbatch, M. North, and G. Zagotto; 'The Synthesis and Conformational Analysis of a Pair of Diastereomeric Cyclic Peptides with Cis and Trans Amide Bonds Respectively' J. Chem. Soc., Chem. Commun., 1993, 641-642.

 

3.     A. Horne, M. North, J.A. Parkinson, and I.H. Sadler; 'The Conformation of Cyclo-[(R)-Cysteinyl-(R)-Cysteine] in Solution; Tetrahedron, 1993, 49, 5891-5904.

 

4.     S. Cumberbatch, M. North, and G. Zagotto; 'The Synthesis and Conformational Analysis of a Pair of Diastereomeric Conformationally Constrained Peptides with Opposite Amide Bond Geometries' Tetrahedron, 1993, 49, 9049-9066.

 

5.     M. North, S. Cumberbatch, and G. Zagotto; 'The synthesis and conformational analysis of a pair of diastereomeric peptides with opposite amide bond geometries' in 'Peptides 1994' Escom, 1995, 509-510.

 

6.     I.G. Jones, W. Jones, and M. North; 'The Synthesis of Conformationally Constrained Peptides and Pseudo-Peptides Incorporating an Endo-(2S, 3R)-2-Amino-3-Carboxy-Norborn-5-ene Residue', Synlett, 1997, 63-65.

 

7.     S. Caveda Cepas and M. North; '1,2-Dithia-5-Azacyclooctan-6-one and Related Compounds: Synthesis and Conformation', Tetrahedron, 1997, 53, 16859-16866.

 

8.     D.E. Hibbs, M.B. Hursthouse, I.G. Jones, W. Jones, K.M.A. Malik, and M. North; 'A Facile Approach for the Synthesis of Pseudo-Peptides Incorporating a (2S, 3R)-2-Amino-Cyclopropane Carboxylic Acid Residue.', Tetrahedron, 1997, 53, 17417-17424.

 

9.     D.E. Hibbs, M.B. Hursthouse, I.G. Jones, W. Jones, K.M.A. Malik, and M. North; 'Synthesis of Peptides and Pseudopeptides Incorporating an endo-(2S, 3R)-Norborn-5-ene Residue as a Turn Inducer' J. Org. Chem., 1998, 63, 1496-1504.

 

10. I.G. Jones, W. Jones, and M. North, 'Conformational Analysis of Peptides and Pseudo-Peptides Incorporating an endo-(2S, 3R)-Norborn-5-ene Residue as a Turn Inducer' J. Org. Chem., 1998, 63, 1505-1513.

 

11. I.G. Jones, and M. North; 'The Use of Norbornene Derivatives in the Synthesis of Conformationally Constrained Peptides and Pseudo-Peptides', Letters in Peptide Science, 1998, 5, 171-173.

 

12. I.G. Jones, W. Jones, and M. North; ‘The Synthesis of Conformationally Constrained Analogues of the ACE Inhibitor Idrapril’, Tetrahedron, 1999, 55, 279-290.

 

13. D. Birch, R.R. Hill, G.E. Jeffs, and M. North; ‘Stereochemical preference for heterochiral coupling controls selectivity in competitive peptide synthesis’, Chem. Commun. 1999, 941-942.

 

14. R.R. Hill, D. Birch, G.E. Jeffs, and M. North; ‘Enantioselection in peptide bond formation’, Org. Biomol. Chem., 2003, 1, 965-972.

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