Bioelectrochemical Systems
  and Engineering
Research Group


Enzymatic Fuel Cells  Bioelectrochemical Systems Biosensors   Nanomaterials 
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Enzymatic Fuel Cells

Enzymatic Biofuel Cells for Implantable Medical Devices

This project is sponsored by EPSRC. The aim of this project is to research and develop a biofuel cell system which provides power for implantable electrically operated devices, and obtain further understanding on enzymatic electrochemical reactions for glucose oxidation and oxygen reduction.

Biofuel cells offer specific advantages over other renewable energy conversion methods. These advantages are particularly attractive in the medical field where the developments in medical science leads to an increasing number of implantable devices, which need miniaturised, implantable and low-power sources to support their operation. Apart from this, biofuel cells have potential applications also on miniaturised electronic devices and environmental applications (such as wastewater treatment). To achieve an efficient power system, research will be carried out on bioelectrocatalysis, transport processes and system integration.

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Enzymatic Fuel Cells with Pyranose-2-Oxidase (P2O)


The aim of this study is to develop enzyme electrodes using P2O and to investigate its potential use in enzymatic fuel cells as alternative to common used enzymes such as Glucose Oxidase. P2O has a wide range of substrate selectivity without an anomeric selectivity which makes it promising for enzymatic biofuel cell anodes. In this study, a mutant P2O with a very low oxygen affinity was used to develop enzymatic fuel cells. Since oxygen plays an essential role in enzymatic glucose oxidation (mainly competing with mediator to accept generated electrons), it is a big advantage to use an enzyme which have low turnover rates for oxygen.



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Last updated in December 2016