{"id":4,"date":"2014-12-10T15:07:39","date_gmt":"2014-12-10T15:07:39","guid":{"rendered":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/?page_id=4"},"modified":"2014-12-10T15:07:39","modified_gmt":"2014-12-10T15:07:39","slug":"publications-jeremy-brown","status":"publish","type":"page","link":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/publications-jeremy-brown\/","title":{"rendered":"Publications, Jeremy Brown"},"content":{"rendered":"<h2>Published:<\/h2>\n<p>E.Leung, C.Schneider, F.Yan, H.Mohi-El-Din, G.Kudla, A.Tuck, W.Wlotzka, V.A.Doronina, R.Bartley, N.J.Watkins, D.Tollervey &amp;<strong> J.D.Brown. <\/strong>Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery. Nucleic Acids Res. \u00a0<strong>42:<\/strong>10698-710.<\/p>\n<p>V.Odon, G.A.Luke, C.Roulston, P.de Felipe, L.Ruan, H.Escuin-Ordinas, <strong>J.D.Brown<\/strong>, M.D.Ryan &amp; A.Sukhodub (2013) APE-type non-LTR retrotransposons of multicellular organisms encode virus-like 2A oligopeptide sequences which mediate translational recoding during protein synthesis. Mol Biol Evol <strong>30<\/strong>:1955-65.<\/p>\n<p>P.Sharma, F.Yan, V.A.Doroinina, H.Escuin-Ordinas, M.D.Ryan &amp; <strong>J.D.Brown<\/strong> (2012) 2A peptides provide distinct solutions to driving stop-carry on translational recoding. Nucleic Acids Res. <strong>40<\/strong>: 3143-51.<\/p>\n<p>P.de Felipe, G.A.Luke, <strong>J.D.Brown<\/strong> &amp; M.D.Ryan (2010) Inhibition of 2A-mediated \u2018cleavage\u2019 of certain artificial polyproteins bearing N-terminal signal sequences. Biotechnol J. <strong>5<\/strong>:213-23.<\/p>\n<p>C.Schneider, E.Leung, <strong>J.D.Brown<\/strong> &amp; D.Tollervey (2009) The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome. Nucleic Acids Res. <strong>37<\/strong>:1127-40.<\/p>\n<p>V.A.Doronina, C.Wu, P.de Felipe, M.S.Sachs, M.D.Ryan &amp; <strong>J.D.Brown<\/strong> (2008) Site-specific release of nascent chains from ribosomes at a sense codon. Mol. Cell. Biol. <strong>28<\/strong>: 4227-39.<\/p>\n<p>R.W.van Nues, E.Leung, J.C.McDonald, I.Dantuluru, &amp; <strong>J.D.Brown <\/strong>(2008) Roles for Srp72p in assembly, nuclear export and function of the signal recognition particle. RNA Biol. <strong>5<\/strong>: 73-83.<\/p>\n<p>R.W.van Nues, &amp; <strong>J.D.Brown<\/strong> (2007) Distant segments of <em>Saccharomyces cerevisiae<\/em> scR1 RNA promote assembly and function of the Signal Recognition Particle. J. Mol. Biol. <strong>368<\/strong>: 677-690.<\/p>\n<p>W.Ng, T.Sergeyenko, N.Zeng,\u00a0 <strong>J.D.Brown<\/strong> &amp; K.Romisch (2007). Characterization of the proteasome interaction with the Sec61 channel in the endoplasmic reticulum J. Cell Sci. <strong>120<\/strong>: 682-91.<\/p>\n<p>C. Zwieb, R.W.van Nues, M.A.Rosenblad<strong>, J.D.Brown<\/strong> &amp; T.Samuelsson (2005). A nomenclature for all signal recognition particle RNAs. RNA, <strong>11<\/strong>: 7-13.<\/p>\n<p>R.W.van Nues, &amp; <strong>J.D.Brown<\/strong>. (2004) <em>Saccharomyces<\/em> SRP RNA secondary structures: a conserved S-domain and expanded Alu-domain. RNA <strong>10<\/strong>: 75-89.<\/p>\n<p>C.Blackwell, C.L.Russell, S.Argimon, A.J.P.Brown &amp; <strong>J.D.Brown<\/strong> (2003). Protein A-tagging for purification of native macromolecular complexes from <em>Candida albicans<\/em>. Yeast <strong>20<\/strong>: 1235-41.<\/p>\n<p>P.de Felipe, L.E.Hughes, M.D.Ryan, &amp; <strong>J.D.Brown<\/strong> (2003). Co-translational, intraribosomal cleavage of\u00a0 polypeptides by Foot-and-mouth Disease Virus 2A peptide. J. Biol. Chem. <strong>278<\/strong>: 11441\u201311448.<\/p>\n<p>L.F.Ciufo &amp; <strong>J.D.Brown<\/strong> (2000). Nuclear export of yeast signal recognition particle lacking Srp54p via the Xpo1p\/Crm1p, NES-dependent, pathway. Current Biology <strong>10<\/strong>: 1256-64.<\/p>\n<p>N.Mason, L.F.Ciufo &amp; <strong>J.D.Brown<\/strong> (2000). Elongation arrest is a physiologically important function of\u00a0 Signal Recognition Particle. The EMBO Journal <strong>19<\/strong>: 4164-74.<\/p>\n<p>D.T.W.Ng, <strong>J.D.Brown<\/strong> &amp; P.Walter (1996). Signal sequences specify the targeting route to the endoplasmic reticulum membrane. J. Cell Biol. <strong>134<\/strong>: 269-278.<\/p>\n<p>P.E.Hodges, S.P.Jackson, <strong>J.D.Brown<\/strong> &amp; J.D.Beggs (1995). Extraordinary sequence conservation of the PRP8 splicing factor. Yeast, <strong>11<\/strong>: 337-342.<\/p>\n<p><strong>J.D.Brown<\/strong>, D.T.Ng, S.C.Ogg, P.Walter (1995). Targeting pathways to the endoplasmic reticulum membrane. Cold Spring Harb Symp Quant Biol, <strong>60<\/strong>: 23-30.<\/p>\n<p><strong>J.D.Brown<\/strong>, B.C.Hann, K.F.Medzihradszky, M.Niwa, A.L.Burlingame &amp; P.Walter (1994). Subunits of the <em>Saccharomyces<\/em> <em>cerevisiae<\/em> signal recognition particle required for its functional expression. The EMBO Journal <strong>13<\/strong>: 4390-4400.<\/p>\n<p><strong>J.D.Brown<\/strong> and J.D.Beggs (1992). Roles of PRP8 protein in the assembly of splicing complexes.\u00a0 The EMBO Journal <strong>11<\/strong>: 3721-9.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Published: E.Leung, C.Schneider, F.Yan, H.Mohi-El-Din, G.Kudla, A.Tuck, W.Wlotzka, V.A.Doronina, R.Bartley, N.J.Watkins, D.Tollervey &amp; J.D.Brown. Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery. Nucleic Acids Res. \u00a042:10698-710. V.Odon, G.A.Luke, C.Roulston, P.de Felipe, L.Ruan, H.Escuin-Ordinas, &hellip; <a href=\"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/publications-jeremy-brown\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1028,"featured_media":6,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-4","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/pages\/4","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/users\/1028"}],"replies":[{"embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/comments?post=4"}],"version-history":[{"count":5,"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/pages\/4\/revisions"}],"predecessor-version":[{"id":10,"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/pages\/4\/revisions\/10"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/media\/6"}],"wp:attachment":[{"href":"https:\/\/www.staff.ncl.ac.uk\/jeremy.brown\/wp-json\/wp\/v2\/media?parent=4"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}