{"id":94,"date":"2021-03-02T14:35:33","date_gmt":"2021-03-02T14:35:33","guid":{"rendered":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/?p=94"},"modified":"2022-03-18T09:59:28","modified_gmt":"2022-03-18T09:59:28","slug":"paper-published-dynamics-of-oct4-in-hpscs","status":"publish","type":"post","link":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/2021\/03\/02\/paper-published-dynamics-of-oct4-in-hpscs\/","title":{"rendered":"Paper published: dynamics of OCT4 in hPSCs"},"content":{"rendered":"\n<p class=\"has-normal-font-size\">Our recent work investigating the dynamics of the pluripotency transcription factor OCT4 has been published in IOP Physical Biology:<\/p>\n\n\n\n<p class=\"has-normal-font-size\"><a href=\"https:\/\/iopscience.iop.org\/article\/10.1088\/1478-3975\/abd22b\">OCT4 expression in human embryonic stem cells: spatio-temporal dynamics and fate transitions<\/a><\/p>\n\n\n\n<p class=\"has-normal-font-size\">We use time-lapse experimental data of OCT4-mCherry fluorescence intensity to quantify the temporal and spatial dynamics of the pluripotency transcription factor OCT4 in a growing hESC colony in the presence and absence of BMP4.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"544\" src=\"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/files\/2021\/03\/workflow2-1024x544.jpg\" alt=\"\" class=\"wp-image-95\" srcset=\"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/files\/2021\/03\/workflow2-1024x544.jpg 1024w, https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/files\/2021\/03\/workflow2-300x159.jpg 300w, https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/files\/2021\/03\/workflow2-768x408.jpg 768w, https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/files\/2021\/03\/workflow2-1536x816.jpg 1536w, https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/files\/2021\/03\/workflow2-2048x1088.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Our recent work investigating the dynamics of the pluripotency transcription factor OCT4 has been published in IOP Physical Biology: OCT4 expression in human embryonic stem cells: spatio-temporal dynamics and fate transitions We use time-lapse experimental data of OCT4-mCherry fluorescence intensity to quantify the temporal and spatial dynamics of the pluripotency transcription factor OCT4 in a &hellip; <a href=\"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/2021\/03\/02\/paper-published-dynamics-of-oct4-in-hpscs\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Paper published: dynamics of OCT4 in hPSCs<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":4649,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-94","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/posts\/94","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/users\/4649"}],"replies":[{"embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/comments?post=94"}],"version-history":[{"count":2,"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/posts\/94\/revisions"}],"predecessor-version":[{"id":110,"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/posts\/94\/revisions\/110"}],"wp:attachment":[{"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/media?parent=94"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/categories?post=94"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.staff.ncl.ac.uk\/laurawadkin\/wp-json\/wp\/v2\/tags?post=94"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}