Publications: Full Papers Book Chapters Reviews
Burgoyne, R.D. & Cheek, T.R. (1985). Is the transient nature of the secretory response of chromaffin cells due to inactivation of Ca2+ channels? FEBS lett. 182, 115-118.
Cheek, T.R. & Burgoyne, R.D. (1985). Effect of activation of muscarinic receptors on intracellular free Ca2+ and secretion in bovine adrenal chromaffin cells. Biochim. Biophys. Acta 846, 167-173.
Baker, E.M., Cheek, T.R. & Burgoyne, R.D. (1985). Cyclic AMP inhibits secretion in bovine adrenal chromaffin cells evoked by carbamylcholine but not by high K+. Biochim. Biophys. Acta 846, 388-393.
Brocklehurst, D., Champion, A.E., Cheek, T.R. & Dewhurst, D.G. (1986). The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer. Tumour Biology 7, 99-104.
Burgoyne, R.D., Cheek, T.R. & Norman, K.M. (1986). Identification of a secretory granule binding protein as caldesmon. Nature 319, 68-73.
Cheek, T.R., Hesketh, J.E., Richards, R.C. & Burgoyne, R.D. (1986). Assembly and characterisation of a multi-component cytoskeletal gel from adrenal medulla. Biochim. Biophys. Acta 887, 164-172.
Harris, B., Cheek, T.R. & Burgoyne, R.D. (1986). Effect of metalloendoproteinase inhibitors on secretion and intracellular free Ca2+ in bovine adrenal chromaffin cells. Biochim. Biophys. Acta 889, 1-5.
Cheek, T.R. & Burgoyne, R.D. (1986). Nicotine-evoked disassembly of cortical actin filaments in bovine adrenal chromaffin cells. FEBS lett. 207, 110-113.
Cobbold, P.H., Cheek, T.R., Cuthbertson, K.S.R. & Burgoyne, R.D. (1987). Calcium transients in single adrenal chromaffin cells detected with aequorin. FEBS lett. 211, 44-48.
Cheek, T.R. & Burgoyne, R.D. (1987). Cyclic AMP inhibits both nicotine stimulated actin disassembly and catecholamine secretion from bovine adrenal chromaffin cells. J. Biol. Chem. 262, 11663-11666.
Burgoyne, R.D. & Cheek, T.R. (1987). Reorganisation of peripheral actin filaments as a prelude to exocytosis. Biosci. Rep. 7, 281-288.
Mason, W.T., Rawlings, S.R., Cobbett, P., Sikdar, S.K., Zorec, R., Akerman, S.N., Benham, C.D., Berridge, M.J., Cheek, T.R. & Moreton, R.B. (1988). Control of secretion in anterior pituitary cells- linking ion channels, messengers and exocytosis. J. Exp. Biol. 139, 287-316.
O'Sullivan, A.J., Cheek, T.R., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1989). Localization and heterogeneity of agonist-induced changes in cytosolic calcium in bovine adrenal chromaffin cells from video imaging of fura-2. EMBO J. 8, 401-411.
Cheek, T.R., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1989). Spatial localization of the stimulus-induced rise in cytosolic calcium in bovine adrenal chromaffin cells: distinct nicotinic and muscarinic patterns. FEBS lett. 247, 429-434.
Cheek, T.R. & Thastrup, O. (1989). Internal calcium mobilization and secretion in bovine adrenal chromaffin cells. Cell Calcium 10, 213-221.
Cheek, T.R., Jackson, T.R., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1989). Simultaneous measurements of cytosolic calcium and secretion in single bovine adrenal chromaffin cells by fluorescent imaging of fura-2 in co-cultured cells. J. Cell Biol. 109, 1219-1227.
Burgoyne, R.D., Cheek, T.R., Morgan, A., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J., Mata, A., Colyer, J., Lee, A.G. & East, J.M. (1989). Distribution of two distinct Ca2+-ATPase like proteins and their relationship to the agonist sensitive calcium store in bovine adrenal chromaffin cells. Nature 342, 72-74.
Corps, A.N., Cheek, T.R., Moreton, R.B., Berridge, M.J. & Brown, K.D. (1989). Single-cell analysis of the mitogen-induced calcium responses of normal and protein kinase C-depleted Swiss 3T3 cells. Cell Regulation 1, 75-86.
Cheek, T.R., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1990). The caffeine-sensitive Ca2+ store in bovine adrenal chromaffin cells; an examination of its role in triggering secretion and Ca2+ homeostasis. FEBS lett. 266, 91-95.
Robb, S., Cheek, T.R., Venter, J.C., Midgley, J.M. & Evans, P.D. (1991). The mode of action and pharmacology of a cloned Drosophila phenolamine receptor. Pest. Sci. 32, 369-371.
Howes, E.A., Cheek, T.R. & Smith, P.J.S. (1991). Long-term growth in vitro of isolated, fully differentiated neurones from the CNS of an adult insect. J. Exp. Biol. 156, 591-605.
Cheek, T.R., Barry, V.A., Berridge, M.J. & Missiaen, L. (1991). Bovine adrenal chromaffin cells contain an InsP3-insensitive but caffeine-sensitive Ca2+ store that can be regulated by intraluminal free Ca2+. Biochem. J. 275, 697-701.
Akerman, S.N., Zorec, R., Cheek, T.R., Moreton, R.B., Berridge, M.J. & Mason W.T. (1991). Fura-2 imaging of TRH and dopamine effects on calcium homeostasis of bovine lactotrophs. Endocrinology 129, 475-488
Vincent, C., Cheek, T.R. & Johnson, M.H. (1992). Cell cycle progession of parthenogenetically activated mouse oocytes to interphase is dependent on the level of internal calcium. J. Cell Sci. 103, 389-396.
Robinson, I.M., Cheek, T.R. & Burgoyne, R.D. (1992). Ca2+ influx induced by the Ca2+-ATPase inhibitors 2,5-Di-(tert-Butyl)-1,4-benzohydroquinone and thapsigargin in bovine adrenal chromaffin cells. Biochem. J.288, 457-463.
Cheek, T.R., Morgan, A., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1993). Spatial localization of agonist-induced Ca2+ entry in bovine adrenal chromaffin cells: different patterns induced by histamine and angiotensin II, and relationship to catecholamine release. J. Cell Sci. 105, 913-921.
Cheek, T.R., McGuinness, O.M., Vincent, C., Moreton, R.B., Berridge, M.J. & Johnson, M.H. (1993). Fertilisation and thimerosal stimulate similar calcium spiking patterns in mouse oocytes but by separate mechanisms. Development119, 179-189.
Cheek, T.R., Moreton, R.B., Berridge, M.J., Stauderman, K.A., Murawsky, M.M. & Bootman, M.D. (1993). Quantal Ca2+ release from caffeine-sensitive stores in adrenal chromaffin cells. J. Biol. Chem. 268, 27076-27083.
Barry, V.A. & Cheek, T.R. (1994). Extracellular ATP triggers two functionally distinct calcium signalling pathways in PC12 cells. J. Cell Sci. 107, 451-462.
Barry, V.A. & Cheek, T.R. (1994). A caffeine- and ryanodine-sensitive intracellular Ca2+ store can act as a Ca2+ source and a Ca2+ sink in PC12 cells. Biochem. J. 300, 589-597.
Robb, S., Cheek, T.R., Hannan, F., Hall, L.M., Midgley, J.M. & Evans, P.D. (1994). Agonist specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems. EMBO J. 13, 1325-1330.
Cheek, T.R., Berridge, M.J., Moreton, R.B., Stauderman, K.A., Murawsky, M.M. & Bootman, M.D. (1994). Quantal Ca2+ mobilisation by ryanodine receptors is due to all-or-none release from functionally discrete intracellular stores. Biochem. J. 301, 879-883.
Cheek, T.R., Murawsky, M.M. & Stauderman, K.A. (1994). Histamine-induced Ca2+ entry precedes Ca2+ mobilisation in bovine adrenal chromaffin cells. Biochem. J. 304, 469-476.
Bootman, M.D., Cheek, T.R., Moreton, R.B., Bennett, D.L. & Berridge, M.J. (1994). Smoothly-graded Ca2+ release from InsP3-sensitive stores in HeLa cells. J. Biol. Chem. 269, 24783-24791.
Bennett, D.L., Cheek, T.R., Berridge, M.J., DeSmedt, H., Parys, J.B., Missiaen, L. & Bootman M.D. (1996). Expression and function of ryanodine receptors in non-excitable cells. J. Biol. Chem. 271, 6356-6362.
Combettes, L., Cheek, T.R. & Taylor, C.W. (1996) Regulation of inositol trisphosphate receptors by luminal Ca2+ contributes to quantal Ca2+ mobilisation. EMBO J. 15, 2086-2093.
Bennett, D.L., Bootman, M.D., Berridge, M.J. & Cheek, T.R. (1998) Ca2+ entry into PC12 cells initiated by ryanodine receptors or inositol 1,4,5-trisphosphate receptors. Biochem. J. 329, 349-357.
Burgoyne, R.D. & Cheek, T.R. (1988). Role of the chromaffin cell cytoskeleton in secretion. In Progress in Catecholamine Mechanisms; Basic Aspects and Peripheral Mechanisms. p253-256. Alan R. Liss, Inc.
Burgoyne, R.D., Cheek, T.R., O'Sullivan, A.J. & Richards, R.C. (1988). Control of the cytoskeleton during secretion. In Molecular Mechanisms in Secretion., Alfred Benzon Symposium 25, p612-627. Eds. N.A.Thorn, M. Treiman, O.H. Petersen, Munksgaard, Copenhagen.
Mason, W.T., Sikdar, S.K., Zorec, Z., Akerman, S., Rawlings, S., Cheek, T.R., Moreton, R.B. & Berridge, M.J. (1989). Ion channels, intracellular calcium and exocytosis: Control of hormone secretion in cultured bovine pituitary lactotrophs. In Secretion and its control. Chapter 14, 225-238. The Rockefeller University Press.
Cheek, T.R. (1990). Investigating the role of calcium ions in triggering secretion from living cells using digital-video imaging microscopy. Trans. R. Microscopical Soc. 1, 533-538.
Cheek, T.R. & Burgoyne, R.D. (1991). The cytoskeleton in secretion and neurotransmitter release. In The Neuronal Cytoskeleton p309-325 Ed R.D Burgoyne. Alan R. Liss. Inc.
Cheek, T.R., Burgoyne, R.D. & Berridge, M.J. (1992). Spatial aspects of the calcium signal that triggers exocytosis revealed by imaging techniques. In Methodological Surveys in Biochemistry and Analysis 21, p287-302, Eds. E. Reid, G.M.W. Cook & J.P. Luzio. Roy. Soc. Chem.
Cheek, T.R. (1993). Calcium signalling and the triggering of secretion in adrenal chromaffin cells. In International Encyclopedia of Pharmacology and Therapeutics, p427-441, Ed C.W. Taylor. Pergamon Press.
Robb, S., Cheek, T.R., Hannan, F.L., Reale, V., Hall, L.M., Midgley, J.M. & Evans, P.D. (1994). Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messengers. In Insect Neurochemistry and Neurophysiology, p 351-354, Eds A.B. Borkovec & M.J. Loeb. CRC Press.
Burgoyne, R.D & Cheek, T.R. (1995). Mechanisms of exocytosis and the central role of calcium. In Neurotransmitter Release and Modulation. p7-21. Eds D.A. Powis & S.J. Bunn. Cambridge University Press.
Friesen, W.O., Cheek, T.R., McGuinness, O.M., Moreton, R.B. & Berridge, M.J. (1995). Analysis of calcium fertilization transients in mouse oocytes. In Methods in Neurosciences: Quantitative Neuroendocrinology vol 28, p388-423. Eds M.J. Johnson & J.D. Veldhuis. Academic Press.
Berridge, M.J., Cheek, T.R., Bennett, D.L. & Bootman, M.D. (1995) Ryanodine receptors and intracellular calcium signalling. In Ryanodine receptors: A CRC Pharmacology & Toxocology Series, Basic and Clinical Aspects. p119-153. Ed V.Sorrentino. CRC Press.
Reviews, commentaries and other selected publications
Baker, E.M., Burgoyne, R.D. & Cheek, T.R. (1985). The effect of forskolin on catecholamine release and intracellular free Ca2+ in bovine adrenal chromaffin cells. J. Physiol. 309, 99P.
Cheek, T.R. & Burgoyne, R.D. (1985). Activation of the muscarinic receptor in bovine adrenal medullary chromaffin cells causes a rise in intracellular Ca2+ without stimulating secretion. Biochem. Soc. Trans.13, 1175-1176.
Cheek, T.R., Richards, R.C., Hesketh, J.E. & Burgoyne, R.D. (1986). Actin-binding proteins of the adrenal medulla and the regulation of cytoskeletal gels. Eur. J. Cell Biol. Suppl 13, 40, 7.
Burgoyne, R.D. & Cheek, T.R. (1987). Role of fodrin in secretion. Nature 326, 448.
Burgoyne, R.D., Cheek, T.R. & O'Sullivan, A.J. (1987). Receptor activation of phospholipase A2 in cellular signalling. Trends Biochem. Sci. 12, 332-333.
Cheek, T.R., Moreton, R.B., Berridge, M.J. & Thastrup, O. (1989). Effect of the calcium mobilizing tumour promotor thapsigargin and an inositol trisphosphate mobilizing agonist on cytosolic calcium in bovine adrenal chromaffin cells. Biochem. Soc. Trans. 17, 94-95.
Corps, A.N., Cheek, T.R., Moreton, R.B., Berridge, M.J. & Brown, K.D. (1989). Down modulation of protein kinase C in Swiss 3T3 fibroblasts potentiates the calcium response to bombesin. Biochem. Soc. Trans.17, 712-713.
Cheek, T.R., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1989). Spatial and temporal aspects of agonist-induced changes in cytosolic calcium in bovine adrenal chromaffin cells revealed by fluorescent imaging. In Methodological Surveys in Biochemistry and Analysis 19, Eds. E. Reid, G.M.W. Cook & J.P. Luzio. Roy. Soc. Chem. 319-320.
Cheek, T.R. (1989). Spatial aspects of calcium signalling. J. Cell Sci. 93, 211-216.
Cheek, T.R., Jackson, T.R., O'Sullivan, A.J., Moreton, R.B., Berridge, M.J. & Burgoyne, R.D. (1990). Spatiallly organized intracellular Ca2+ signals in response to different secretagogues in adrenal chromaffin cells. Clin. Neuropharmacol. 13, 442-443.
Cheek, T.R. (1991). Calcium regulation and homeostasis. Curr. Opin. Cell Biol. 3, 199-205.
Burgoyne, R.D & Cheek, T.R. (1991). Locating intracellular calcium stores. Trends Biochem Sci. 16, 319-320.
Cheek, T.R. (1991). Calcium signalling and the triggering of secretion in adrenal chromaffin cells. Pharmac. Ther. 52, 173-189.
Missiaen, L & Cheek, T.R. (1992). Ca2+ measurements with fluorescent indicators in permeabilized cells. Trends Cell Biol. 2, 6.
Burgoyne, R.D., Morgan, A., Robinson I., Pender, N. & Cheek, T.R. (1993). Exocytosis in adrenal chromaffin cells. J. Anat. 183, 309-314.
Cheek, T.R. & Barry, V.A. (1993). Stimulus-secretion coupling in excitable cells: a central role for calcium. J. Exp. Biol. 184, 183-196.
Evans, P.D., Robb, S., Cheek, T.R., Reale, V., Hannan, F.L., Swales, L., Hall, L.M. & Midgley, J.M. (1995). Agonist-specific coupling of G-protein-coupled receptors to second messenger systems. In Current Neurochemical and Pharmacological Aspects of Biogenic Amines. Prog. Brain Res. 106, 259-268
Bennett, D.L., Petersen, C.C.H. & Cheek, T.R. (1995). Cracking Icrac in the eye. Curr. Biol. 5, 1225-1228.
