Our recent work investigating the dynamics of the pluripotency transcription factor OCT4 has been published in IOP Physical Biology:
OCT4 expression in human embryonic stem cells: spatio-temporal dynamics and fate transitions
We use time-lapse experimental data of OCT4-mCherry fluorescence intensity to quantify the temporal and spatial dynamics of the pluripotency transcription factor OCT4 in a growing hESC colony in the presence and absence of BMP4.
