aPKC Cycles between Functionally Distinct PAR Protein Assemblies
to Drive Cell Polarity
Congrats and thank you all for the hard work
Thanks to Edwin Munro for a really clear review of our work in collaboration with Goehrings’ lab and that of Dickinson et al. (2017) and Wang et al. (2017) , all showing how PAR protein oligomerization can dynamically couple protein diffusion and transport by cortical flow to control kinase activity gradients and polarity in the C. elegans zygote.
Protein Clustering Shapes Polarity Protein Gradients