aPKC Cycles between Functionally Distinct PAR Protein Assemblies

to Drive Cell Polarity

Rodriguez et al. (2017)

Congrats and thank you all for the hard work

Thanks to Edwin Munro for a really clear review of our work in collaboration with Goehrings’ lab and that of Dickinson et al. (2017) and Wang et al. (2017) , all showing how PAR protein oligomerization can dynamically couple protein diffusion and transport by cortical flow to control kinase activity gradients and polarity in the C. elegans zygote.

Protein Clustering Shapes Polarity Protein Gradients

Munro (2017)