The Yue lab is part of the Newcastle Structural Biology Laboratory of the Newcastle University Biosciences Institute, and allies with the Newcastle Centre for Rare Diseases
Our Missions
We explore how genetic defects lead to metabolic diseases, using biochemistry, structural biology and chemical biology.
We launch target enablement, hit discovery and hit-to-lead programmes for inhibitors and stabilisers of metabolic enzymes.
We envision the development of small molecule therapeutics through working with clinicians, industry and patient groups.
Our Funders
Our Science↗
More about our approaches in structural biology and drug discovery
Latest Papers ↗
Links to our latest publications and preprints